I will hope and dream that this might someday lead to more mmo/12-button mice on the market, or at least the ability to customize them without relying on their proprietary software.

Definitely! I feel like this was fairly common knowledge even a decade ago and why people would quickly rebound back to previous size and strength when returning to fitness- muscle memory due to myonuclei persisting even when the actual tissue atrophies. I guess this is an additional state of memory for the body. Super neat!